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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL3
All Species:
18.18
Human Site:
S319
Identified Species:
26.67
UniProt:
Q13618
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13618
NP_003581.1
768
88930
S319
T
M
C
E
C
M
S
S
Y
L
R
E
Q
G
K
Chimpanzee
Pan troglodytes
XP_001167451
757
87889
S308
T
M
C
E
C
M
S
S
Y
L
R
E
Q
G
K
Rhesus Macaque
Macaca mulatta
XP_001109600
746
86448
S297
T
M
C
E
C
M
S
S
Y
L
R
E
Q
G
K
Dog
Lupus familis
XP_534586
746
86477
S297
T
M
C
E
C
M
S
S
Y
L
R
E
Q
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLV5
768
88930
C319
T
M
C
E
C
M
S
C
Y
L
R
E
Q
G
K
Rat
Rattus norvegicus
Q9JJ31
780
90872
E316
P
M
L
K
D
L
E
E
H
I
I
S
A
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512511
642
74121
V213
E
G
E
G
K
N
P
V
D
Y
I
Q
G
L
L
Chicken
Gallus gallus
XP_422620
768
88957
S319
T
M
C
E
C
M
S
S
Y
L
R
E
Q
G
K
Frog
Xenopus laevis
Q6DE95
768
88933
L319
T
M
C
E
C
M
S
L
Y
L
R
E
Q
G
K
Zebra Danio
Brachydanio rerio
NP_955985
766
89011
W317
T
M
C
E
C
M
S
W
Y
L
R
E
Q
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
N341
D
L
K
S
I
L
E
N
H
I
L
H
Q
G
T
Honey Bee
Apis mellifera
XP_625079
767
89385
Q316
T
V
C
D
C
V
S
Q
F
L
K
E
Q
G
R
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
E325
A
L
L
K
A
V
S
E
Y
L
N
E
T
G
S
Sea Urchin
Strong. purpuratus
XP_001178314
675
78472
G246
S
S
Y
L
R
E
Q
G
K
A
L
V
Q
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
Q306
P
V
A
N
I
F
K
Q
H
V
T
A
E
G
N
Baker's Yeast
Sacchar. cerevisiae
P53202
744
86097
V299
S
S
E
E
K
Y
R
V
T
V
I
E
S
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
97.1
96.8
N.A.
99.4
26.4
N.A.
83.1
99.6
98.5
95.9
N.A.
28.4
77.2
49.6
67
Protein Similarity:
100
98
97.1
96.8
N.A.
99.6
49.4
N.A.
83.3
99.7
99.2
98.3
N.A.
52.4
87.5
69.1
76.9
P-Site Identity:
100
100
100
100
N.A.
93.3
13.3
N.A.
0
100
93.3
93.3
N.A.
13.3
53.3
33.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
40
N.A.
6.6
100
93.3
93.3
N.A.
46.6
93.3
53.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
7
0
0
0
0
7
0
7
7
0
0
% A
% Cys:
0
0
57
0
57
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
7
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
7
0
13
57
0
7
13
13
0
0
0
69
7
7
7
% E
% Phe:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
7
0
7
0
0
0
7
0
0
0
0
7
82
0
% G
% His:
0
0
0
0
0
0
0
0
19
0
0
7
0
0
0
% H
% Ile:
0
0
0
0
13
0
0
0
0
13
19
0
0
7
0
% I
% Lys:
0
0
7
13
13
0
7
0
7
0
7
0
0
0
57
% K
% Leu:
0
13
13
7
0
13
0
7
0
63
13
0
0
7
13
% L
% Met:
0
57
0
0
0
50
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
7
0
7
0
0
7
0
0
0
7
% N
% Pro:
13
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
7
13
0
0
0
7
69
0
0
% Q
% Arg:
0
0
0
0
7
0
7
0
0
0
50
0
0
0
7
% R
% Ser:
13
13
0
7
0
0
63
32
0
0
0
7
7
0
7
% S
% Thr:
57
0
0
0
0
0
0
0
7
0
7
0
7
0
7
% T
% Val:
0
13
0
0
0
13
0
13
0
13
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
7
0
0
57
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _